The Guiding Significance of Pupil Monitoring in the Perioperative Period

Yangzhou University

Status

Completed

Conditions

Pupil Light Reflection

Pupil Diameter

Pupil Contraction Rate

Treatments

Procedure: pupil's light and pupil diameter

Study type

Interventional

Funder types

Other

Identifiers

NCT04820374

20210318

Details and patient eligibility

About

The pupil diameter is affected by both sympathetic and parasympathetic nerves, and its latency and response amplitude mainly reflect the functional status of the parasympathetic nerve. Clinically, the diagnosis of neurological diseases can often be made based on changes in pupils.

An appropriate depth of anesthesia can cause minimal damage to the body after surgery, thereby reducing the impact on brain function and cognitive function.

The occurrence of postoperative delirium will have adverse effects on the prognosis of patients, such as prolonging the hospital stay, increasing the mortality of patients after surgery, and increasing early postoperative cognitive dysfunction.

Enrollment

80 patients

Sex

All

Ages

65 to 95 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Elderly patients undergoing general anesthesia for tracheal intubation, aged ≥65 years, operation time ≥2 hours, ASA classification I-III, and postoperative hospital stay for at least one week.

Exclusion criteria

It is known that this study involves persons who are allergic to general anesthetics;
Patients with previous eye diseases;
Head and neck surgery is not conducive to measurement;
Patients with preoperative MMSE score less than 24 points or dementia due to various diseases;
Patients planning to undergo neurosurgery;
Those who use sedatives or antipsychotics before surgery;
Patients with known central nervous system diseases, such as mental illness; Patients with hearing or vision impairment and unable to communicate normally.