The Health Benefits of Indoor Air Filtration Among Children

Tiantian Li

Status: Completed

Conditions: Protective Effect of Air Purifier on Children's Health

Treatments: Behavioral: Sham Air Purifiers; Behavioral: Air Purifiers

Study type: Interventional

Funder types: Other

Identifiers

NCT04835337

202032

Details and patient eligibility

About

This study aims to explore the health benefits of air purifier on the impact of air pollutants on children's health.

Full description

From April 2021 to December 2021, researchers conduct a randomized double-blind crossover trial on about 100 healthy children in Jiaozuo City, Henan Province. The children are divided into two groups according to their classes and alternated the use of true or sham purifiers devices, including air purifiers and fresh air ventilation. Air purifiers are installed in the classroom and bedrooms of the children. Fresh air ventilation is installed in the classroom. A total of 4 epidemiological surveys are conducted on the subjects, with an interval of 60 days or more. All participants and research staffs were blinded to the group assignment. In addition, air pollutant exposure monitoring, questionnaire surveys, physical examinations, and biological sample collection are conducted on the research subjects each time. The biological samples are further tested for the concentration levels of related biomarkers such as the respiratory system, cardiovascular system, metabolic system, and nervous system. Furthermore, comprehensive evaluation of children's behavioral ability is also carried out. Ambient PM2.5 and indoor PM2.5 exposure concentrations are monitored in the study.

Enrollment: 105 patients

Sex: All

Ages: 10 to 12 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 10 ≤ 12 years old
• Volunteer to participate in this study

Exclusion criteria

• Current and past medical history, including asthma, childhood diabetes, childhood hypertension, behavior-related diseases
• Students who plan to transfer or move within six months
• Unable to cooperate with follow-up

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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105 participants in 2 patient groups

Air purifier

Experimental group

Description:

Participants in this group receive an intervention of real air purifiers placed in the indoor environment.

Treatment:

Behavioral: Air Purifiers

Control

Sham Comparator group

Description:

Participants in this group receive an intervention of sham air purifiers, we just remove the filter in the purifiers, and the other treatments are the same as the real purification group.

Treatment:

Behavioral: Sham Air Purifiers