The Hypoalgesic Effects of Low Load Blood Flow Restriction Training (BFRT)

University of West Attica

Status: Not yet enrolling

Conditions: Healthy

Treatments: Other: Sham Blood flow restriction training; Other: Blood flow restriction training

Study type: Interventional

Funder types: Other

Identifiers

NCT05446103

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Details and patient eligibility

About

A randomized controlled trial comparing the immediate effects of upper limb low-load blood flow restriction training (BFRT) with high load sham-BFRT on hypoalgesia and perceptual response in healthy adults

Full description

Healthy individuals will be randomized to one of two groups. A target of 40 patients for enrollment has been set for 80% power, p<0.05 (Effect size= 1). A single Intervention will be used (40 minutes).

Intervention Group: A single exercise of elbow flexion with Blood Flow Restriction (30-15-15-15 reps) using 30% of 1 Repetition Maximum.

Control Group: A single exercise of elbow flexion with sham Blood Flow Restriction (4x10 reps) using 65% of 1 Repetition Maximum.

Primary outcome: pressure pain thresholds on quadriceps, biceps, lateral epicondyle and upper trapezius (bilateral).

Secondary outcomes: difference in perceptual response (exertion), change in blood pressure

Enrollment: 40 estimated patients

Sex: All

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• BMI< 30
• able to perform full elbow flexion and extension

Exclusion criteria

• shoulder tendinopathy,
• cervical radiculopathy,
• rheumatoid arthritis,
• neurological deficit,
• serious cardiovascular diseases,
• venous deficiency,
• history of heart surgery,
• cancer history,
• breast surgery,
• orthopaedic surgeries during the last 6 months,
• thrombosis,
• diabetes,
• body mass Index ≥ 30,
• Crohn syndrome,
• family or personal history of pulmonary embolism

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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40 participants in 2 patient groups

BFR

Experimental group

Description:

20 healthy individuals will be assigned to perform elbow flexion exercises with low-load resistance BFR training (30% of 1 RM)

Treatment:

Other: Blood flow restriction training

Sham BFR

Sham Comparator group

Description:

20 healthy individuals will be assigned to perform elbow flexion exercises with high-load resistance training with sham BFR (65% of 1 RM)

Treatment:

Other: Sham Blood flow restriction training