The Immune Response to Stroke

University of Oslo

Status: Enrolling

Conditions: Stroke, Acute; Dementia

Treatments: Other: Analysis of post-stroke immune responses

Study type: Observational

Funder types: Other

Identifiers

NCT05277129

2019/1252

Details and patient eligibility

About

Some patients develop cognitive decline after a stroke, but we don't always understand the mechanisms. It has been proposed that a proportion of the patients develop an autoimmune immune response, and that this could potentially explain the cognitive decline in some of the patients. The current study aims to investigate this hypothesis in a subgroup of patients with stroke.

Enrollment: 40 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Stroke < 72 h
• Age > 18 years

Exclusion criteria

• Brain hemorrhage verified by CT or MRI scan
• Previous or present immunological disease or other serious comorbidity
• Ongoing immune respons after infection or vaccination < 1 month
• Cognitive without ability to understand and/or give an informed consent to participate in the study

Trial design

40 participants in 1 patient group

Stroke patients

Treatment:

Other: Analysis of post-stroke immune responses