The Impact of a Fast Diet and Calorie Mimetic Supplements on Epigenetic Aging

TruDiagnostic

Status and phase: Unknown; Phase 2

Conditions: Aging

Treatments: Behavioral: Fasting Mimicking Diet; Dietary Supplement: Peak Human Labs calorie mimetic supplement

Study type: Interventional

Funder types: Industry; Other

Identifiers

NCT04962464

TD-EA-001

Details and patient eligibility

About

This is a prospective randomized clinical study of 50 patients to evaluate the fasting mimicking diet program by Prolon with a calorie mimetic supplement from Peak Human Labs. This study will be evaluating the effectiveness of the combined intervention over a three month program.

The study will assess the effects that the program has on the participants' biological aging.

Enrollment: 100 estimated patients

Sex: All

Ages: 16+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Healthy individuals
• Age > 16 years

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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100 participants in 4 patient groups

Fasting Mimicking Diet + Supplement / Usual Routine

Experimental group

Description:

Participants in will be asked to begin the Peak Human Labs calorie mimetic supplement. They will also begin on day 1 the 5 day Fasting Mimicking Diet Program. Participants will continue the supplementation for the 90 days and repeat the 5 day Fasting Mimicking Diet Program on days 1, 29 and 57. Starting at day 91, they will return to their usual daily routine.

Treatment:

Dietary Supplement: Peak Human Labs calorie mimetic supplement

Behavioral: Fasting Mimicking Diet

Supplement / Usual Routine

Experimental group

Description:

Participants will be asked to begin the Peak Human Labs calorie mimetic supplement. Participants will continue the supplementation for 90 days. Starting at day 91, they will return to their usual daily routine.

Treatment:

Dietary Supplement: Peak Human Labs calorie mimetic supplement

Usual Routine / Fasting Mimicking Diet + Supplement

Experimental group

Description:

Participants will have no intervention for the first 90 days, during which they will be asked not to start a new fasting program supplement. At day 91, they will begin the 5-day Fasting Mimicking Diet Program and start the Peak Human Labs calorie mimetic supplement. Participants will continue the supplementation for 90 days and repeat the 5-day Fasting Mimicking Diet Program on days 91, 120, and 148.

Treatment:

Dietary Supplement: Peak Human Labs calorie mimetic supplement

Behavioral: Fasting Mimicking Diet

Usual Routine / Supplement

Experimental group

Description:

Participants will have no intervention for the first 90 days, during which they will be asked not to start a new fasting program supplement. At day 91,start the Peak Human Labs calorie mimetic supplement. Participants will continue the supplementation for 90 days.

Treatment:

Dietary Supplement: Peak Human Labs calorie mimetic supplement