The Impact of Adequate Water Intake on Exercise Performance and Mood in Women and Men (WEXMO)

Arizona State University (ASU)

Status: Completed

Conditions: Dehydration; Mood

Treatments: Behavioral: Increase water consumption; Behavioral: Maintain adequate water consumption

Study type: Interventional

Funder types: Other

Identifiers

NCT05033665

STUDY00013646

Details and patient eligibility

About

Dehydration is defined as the state of water deficit due to excessive water losses and/or small water intake. Underhydration is the result of inadequate water intake leading to activation of water hormonal homeostasis, characterized by elevated vasopressin, lower urinary output, and concentrated urine without any measurable changes in total body water. It is well established that dehydration (water deficit) decreases exercise performance and worsens mood, mainly in women. However, the impact of increased water intake in underhydrated individuals on their exercise capacity and mood is not known.

The aim of the proposed study is to investigate the impact of increased water intake in underhydrated individuals on aerobic exercise performance and mood in both women and men.

Enrollment: 217 patients

Sex: All

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy adults
• Residence in Arizona

Exclusion criteria

• Use of diuretics
• Use of anti-depressive medication
• Current pregnancy or lactation
• Current use of injectable insulin
• Diagnosed with irritable bowel syndrome
• Do not pass the Physical Activity Readiness Questionnaire for Everyone (PAR-Q) screening

Trial design

Primary purpose: Prevention

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

217 participants in 2 patient groups

Euhydrated

Active Comparator group

Description:

Afternoon urine osmolality \< 800 mmol/kg or urine specific gravity \< 1.020.

Treatment:

Behavioral: Maintain adequate water consumption

Underhydrated

Experimental group

Description:

Afternoon urine osmolality ≥ 800 mmol/kg or urine specific gravity ≥ 1.020.

Treatment:

Behavioral: Increase water consumption