The Impact of Antibiotic Prophylaxis on Incidence of Post-bronchoscopy Fever and Change of Serum Cytokines

Seoul National University

Status and phase: Completed; Phase 4

Conditions: Fever; Pneumonia

Treatments: Drug: oral amoxicillin/clavulanate 1g (875/125mg); Drug: control

Study type: Interventional

Funder types: Other

Identifiers

NCT01089218

postFB fever

Details and patient eligibility

About

Fever can develop after fiberoptic bronchoscopy (FB) in about 2.5 - 16 % of adult patients. We evaluated the impact of oral amoxicillin/clavulanate (AC) on incidence of postbronchoscopic fever and pneumonia.

Full description

For the population being undergone with bronchoscopy, the clinical signs and procedural measures for complication of bronchoscopy and cytokines will be checked.

Enrollment: 241 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• adult patients (aged 18 years or older) who underwent FB

Exclusion criteria

• concurrent treatment with antibiotics or systemic corticosteroid

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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241 participants in 2 patient groups

control

No Intervention group

Description:

control without intervention

Treatment:

Drug: control

Amoxicillin/clavulanate

Active Comparator group

Treatment:

Drug: oral amoxicillin/clavulanate 1g (875/125mg)