The Impact of Artificial Sunlight on Human Sleep and Circadian Rhythms

VA Palo Alto Health Care System

Status: Completed

Conditions: Circadian Dysregulation; Mood; Sleep

Treatments: Device: Light

Study type: Interventional

Funder types: Other U.S. Federal agency; Other

Identifiers

NCT03636360

Sunlike

Details and patient eligibility

About

The purpose of this study is to examine, in healthy controls, whether LED lighting that has a color spectrum similar to that of sunlight is able to differentially impact mood, circadian rhythms, sleep, and behavior, as compared to standard fluorescent lighting.

Enrollment: 10 patients

Sex: All

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Good self-reported health
• Normal color vision

Exclusion criteria

• No sleep disorders
• No extreme chronotype
• Regular smoker
• Significant hearing loss
• Depression
• Alcohol use disorder
• Use of illegal drugs
• Pregnant

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

---

10 participants in 4 patient groups, including a placebo group

LED - Sunlike

Experimental group

Description:

LED lighting with spectral pattern similar to that of sunlight

Treatment:

Device: Light

Fluorescent

Active Comparator group

Description:

Fluorescent light at same illuminance (lux) as LED light

Treatment:

Device: Light

Dim

Placebo Comparator group

Description:

Dim fluorescent light with same spectrum as "Fluorescent" condition

Treatment:

Device: Light

LED

Active Comparator group

Description:

Standard LED lighting

Treatment:

Device: Light