The Impact of Blood Flow Restriction (BFR) on Exercise and Hemodynamic Responses

The University of Texas System (UT)

Status: Terminated

Conditions: Hemodynamic Response; Exercise Training

Treatments: Device: BStrong Bands; Device: Hokanson Cuffs

Study type: Interventional

Funder types: Other

Identifiers

NCT03540147

2017-10-0074

Details and patient eligibility

About

The impact of blood flow restriction (BFR) on exercise and hemodynamic responses will be studied. The use of BFR will be studied during yoga and low-intensity aerobic exercise in healthy subjects with no history of chronic illness ranging from 18-40 years of age. This study will evaluate several conditions related to cardiovascular physiology in order to determine the safety and efficacy of this type of exercise training. First, the effects of two distinct types of BFR cuffs (BStrong and Hokanson) will be studied during low-intensity aerobic exercise on vascular function. Second, the effect of yoga will be studied with and without the use of BStrong bands on vascular function. Outcome measures include acute effects on endothelial function i.e. flow-mediated dilation, arterial stiffness, beat-by-beat blood pressure, heart rate, RPE (rate of perceived exertion), and blood lactate. For this intervention, the BFR cuffs will be used during exercise to evaluate its safety and efficacy. Since BFR is becoming a widely popular method of exercise, it is important to study its safety and hemodynamic effects.

Full description

Participants will be tested a total of 5 times; twice for the yoga portion and thrice for the aerobic exercise (walking) portion. Outcome measures will be consistent across the five visits and will take approximately 2.5 hours to complete. The order of the five separate sessions will be randomized such that the participant cannot expect which condition they will be performing.

Enrollment: 20 patients

Sex: All

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy adults

Exclusion criteria

• Pregnancy
• A recent illness, recent surgery, or any medical intervention
• history of diabetes, heart disease, or other cardiovascular problems

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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20 participants in 5 patient groups

Exercise with Hokanson cuffs

Experimental group

Description:

Participants will walk on the treadmill with Hokanson cuffs inflated.

Treatment:

Device: Hokanson Cuffs

Exercise with BStrong Bands

Experimental group

Description:

Participants will walk on the treadmill with BStrong bands inflated.

Treatment:

Device: BStrong Bands

Exercise without inflated bands/cuffs

Sham Comparator group

Description:

Participants will walk on the treadmill with non-inflated BStrong bands.

Treatment:

Device: BStrong Bands

Yoga poses with BStrong bands inflated

Experimental group

Description:

Participants will perform 15-20 yoga poses with BStrong bands inflated.

Treatment:

Device: BStrong Bands

Yoga poses with BStrong bands uninflated

Sham Comparator group

Description:

Participants will perform 15-20 yoga poses with uninflated BStrong bands.

Treatment:

Device: BStrong Bands