The Impact of Chokeberry Bioproducts on Metabolic Parameters and Antioxidant Potential

Medical University of Bialystok

Status: Completed

Conditions: Hypertension; Hypercholesterolemia; Diabetes Mellitus; Obesity; Diet, Healthy

Treatments: Other: Dietary intervention with chokeberry juices and fibers; Other: Dietary intervention with chokeberry juices

Study type: Interventional

Funder types: Other

Identifiers

NCT06435130

MUBialystok2

Details and patient eligibility

About

Chokeberry can be used both in the prevention and treatment of various metabolic disorders due to its high antioxidant properties. The study assessed for the first time the synergistic effect of chokeberry juice and chokeberry fiber on selected metabolic and anthropometric parameters. 102 people (67 women and 35 men) took part in the intervention study. After 8 weeks of intervention with chokeberry juice and another 4 weeks of intervention with chokeberry juice and fiber, a change in waist circumference, blood pressure, glucose, glycated hemoglobin, LDL cholesterol, aspartate transaminase (AST) and the level of antioxidant potential was observed.

Enrollment: 102 patients

Sex: All

Ages: 30 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• age 30-65 years,
• low or moderate physical activity.

Exclusion criteria

• age <30 and >65 years,
• high physical activity,
• obesity (class II),
• diabetes (all types),
• gastric ulcer,
• acute or chronic gastritis,
• intestinal diseases, including inflammatory bowel diseases and functional intestinal disorders,
• taking hypoglycemic, lipid-lowering, immunosuppressive, anticoagulant and antihypertensive drugs, use of steroid therapy,
• high physical activity,
• pregnancy,
• breastfeeding.

Trial design

Primary purpose: Prevention

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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102 participants in 1 patient group

Dietary intervention with chokeberry juice and fibre

Experimental group

Description:

Study participants consumed 100 mL of chokeberry juice daily for 8 weeks. After 8 weeks, participants consumed 100 ml of chokeberry juice and 10 g of chokeberry fiber daily for 4 weeks.

Treatment:

Other: Dietary intervention with chokeberry juices

Other: Dietary intervention with chokeberry juices and fibers