The Impact of Diet Liberalization on Bowel Preparation for Colonoscopy

Thomas Jefferson University

Status: Completed

Conditions: Colonic Diseases

Treatments: Other: Low residue breakfast and lunch; Other: Clear liquids

Study type: Interventional

Funder types: Other

Identifiers

NCT01876576

12D.247

Details and patient eligibility

About

This study will evaluate the expansion of dietary options from clear liquids the entire day to a low reside breakfast and lunch for patients prior to undergoing bowel preparation with MoviPrep® and its effect on preparation quality for colonoscopy.

Full description

This study will evaluate the expansion of dietary options from clear liquids the entire day to a low reside breakfast and lunch for patients prior to undergoing bowel preparation with MoviPrep® and its effect on preparation quality for colonoscopy. MoviPrep® is a commercially available 2 liter bowel purgative for use before colonoscopy in adults 18 years of age or older that is comprised of polyethylene glycol-electrolyte solution (PEG-ELS) plus sodium sulfate, sodium ascorbate, and ascorbic acid.

Enrollment: 175 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Elective outpatients > 18 yrs undergoing colonoscopy

Exclusion criteria

• Unable or unwilling to give informed consent
• Age < 18 years
• Pregnant
• Breast feeding
• Gastroparesis - established or suspected
• Pseudo-obstruction - established or suspected
• Severe constipation (< 1 BM a week)
• Bowel obstruction
• Colon resection
• Chronic nausea or vomiting
• Known Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency
• PEG allergy
• Significant psychiatric illness

Trial design

175 participants in 2 patient groups

clear liquids

Active Comparator group

Description:

Clear liquids the day of bowel preparation up to 2.5 hrs before colonoscopy

Treatment:

Other: Clear liquids

low residue diet

Active Comparator group

Description:

Low residue breakfast and lunch up to 1pm; clear liquids thereafter up to 2.5 hrs before colonoscopy

Treatment:

Other: Low residue breakfast and lunch