The Impact of Distraction on Adenoma Detection Rate

Dalin Tzu Chi General Hospital

Status: Completed

Conditions: Adenoma

Treatments: Procedure: water immersion; Procedure: Water exchange; Procedure: Air insufflation

Study type: Interventional

Funder types: Other

Identifiers

NCT02978664

DalinHsieh201401

Details and patient eligibility

About

The investigators will review video-recordings of three randomized, controlled trials (NCT01535326, 01699399, and 01894191) comparing air insufflation, water immersion and water exchange during colonoscopy. These studies were all conducted at Buddhist Dalin Tzu Chi Hospital.

Full description

The investigators will review video-recordings of three randomized controlled trials (NCT01535326, 01699399, and 01894191) comparing air insufflation, water immersion and water exchange. These studies were conducted at Buddhist Dalin Tzu Chi Hospital. Permission will be obtained from the local Institutional Review Board (IRB) to review, analyze and report de-identified findings.

Two experienced endoscopists (YHH and CWT) performed all the recorded colonoscopies. Recordings will be selected for review if they are complete examinations; include clear identification of the appendiceal orifice and/or the ileocecal valve, indicating arrival at the cecum; available in the appropriate format for video editing; and contain no patient or endoscopist identifiers. Patients with incomplete recordings and a history of bowel resection will be excluded from analysis. The included video recordings will be edited to remove the insertion phase to blind the study reviewer to the insertion techniques. One blinded reviewer uninvolved in the performance of the colonoscopies will be in charge of evaluating the selected videos, using the criteria described by Yung et al

Enrollment: 500 patients

Sex: All

Ages: 20 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• if they are complete examinations; include clear identification of the appendiceal orifice and/or the ileocecal valve, indicating arrival at the cecum; available in the appropriate format for video editing; and contain no patient or endoscopist identifiers.

Exclusion criteria

• Patients with incomplete recordings and a history of bowel resection will be excluded from analysis.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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500 participants in 3 patient groups

Air insufflation

Active Comparator group

Description:

Air insufflation will be used throughout whole procedure of colonoscopy

Treatment:

Procedure: Air insufflation

water immersion

Active Comparator group

Description:

Water will be infused during the insertion phase and removed during withdrawal phase of colonoscopy

Treatment:

Procedure: water immersion

water exchange

Active Comparator group

Description:

Water will be infused and removed during insertion phase of colonoscopy

Treatment:

Procedure: Water exchange