The Impact of Intraoperative Systemic Lidocaine Infusion on Chronic Postoperative Pain After Video-assisted Thoracic Surgery (VATS)

Yonsei University

Status: Completed

Conditions: Lung Cancer(Primary, Metastatic); Benign Lung Mass Requiring Operation

Treatments: Drug: Normal saline infusion; Drug: Systemic intravenous lidocaine infusion

Study type: Interventional

Funder types: Other

Identifiers

NCT02006966

4-2013-0693

Details and patient eligibility

About

Systemic lidocaine infusion may improve the patients' chronic post surgical pain after video-assisted thoracic surgery

Enrollment: 168 patients

Sex: All

Ages: 20 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age between 20 and 65 years
• ASA class 1 and 2
• Patients who are scheduled for video-assisted thoracic surgery

Exclusion criteria

• Allergy to local anesthetics or contraindication to use of lidocaine
• Pregnancy
• Severe cardiovascular disease
• Renal failure
• Liver failure
• Neurologic and psychologic disease
• Chronic treatment with analgesics or chronic pain patients
• Previous history of thoracic surgery (open or video-assisted)
• Patients' refusal

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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168 participants in 2 patient groups

Group L

Experimental group

Description:

Intravenous lidocaine infusion group

Treatment:

Drug: Systemic intravenous lidocaine infusion

Group C

Active Comparator group

Description:

Intravenous normal saline infusion - control group

Treatment:

Drug: Normal saline infusion