The Impact of Light, Electrical, and Magnetic Neuroregulation Interventions on Sleep-wake Disorders

Soochow University

Status: Enrolling

Conditions: REM Sleep Behavior Disorder; Narcolepsy; Insomnia Chronic

Treatments: Device: Transcranial Magnetic Stimulation

Study type: Interventional

Funder types: Other

Identifiers

NCT06797284

LK2024002

Details and patient eligibility

About

Carry out precise and effective neuromodulation interventions, and develop new neuromodulation technologies for sleep disorders. Use phototherapy, transcranial electrical/magnetic stimulation and other therapies to conduct self-controlled intervention studies on insomnia, narcolepsy, and rapid eye movement sleep behavior disorder .

Enrollment: 20 estimated patients

Sex: All

Ages: 8 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with insomnia, narcolepsy,and RBD that have been clearly diagnosed by specialists should sign the informed consent form.

Exclusion criteria

1. Patients with major neurological diseases such as multi-infarct dementia, Huntington's disease, normal pressure hydrocephalus, brain tumors, progressive supranuclear palsy, epilepsy, subdural hematoma, multiple sclerosis, or those who have sustained neurological dysfunction or known structural brain abnormalities after significant head trauma are excluded.
2. A history of major depressive disorder or bipolar disorder within the past year, as defined in DSM-IV criteria. A history of schizophrenia (meeting DSM-IV criteria).
3. History of severe drug or alcohol abuse within the past year;
4. Any significant systemic illness or unstable medical condition that may make it difficult to comply with the protocol, such as severe autoimmune diseases or a history of cancer.
5. Have significant hearing, visual, or cognitive impairments, or are unable to participate in interviews in a meaningful way.

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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20 participants in 1 patient group

Intervention Group

Experimental group

Description:

transcranial magnetic stimulation or transcranial direct current stimulation or daytime timed bright light exposure

Treatment:

Device: Transcranial Magnetic Stimulation