The Impact of Misclassification of Obesity by Body Mass Index on Mortality in Patients With Chronic Kidney Disease

Buddhist Tzu Chi Medical Foundation

Status: Completed

Conditions: Chronic Kidney Diseases; Obesity

Treatments: Other: No intervention

Study type: Observational

Funder types: Other

Identifiers

NCT03285074

99-IRB-016-XD

Details and patient eligibility

About

Unlike the general population, a higher body mass index (BMI) is associated with greater survival among patients with chronic kidney disease (CKD). However, obesity is defined as excess body fat that associated with clearly elevated health risks according to the World Health Organization. In addition, muscle wasting is prevalent among CKD subjects. Thus, we hypothesized that different definition of obesity, based on BMI or body fat percentage, might have different impact on clinical outcomes among CKD population.

Enrollment: 326 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Subjects with non-dialysis CKD defined as estimated glomerular filtration rate (eGFR) <60 ml/min/1.73 m2

Exclusion criteria

• subjects with liver cirrhosis
• subjects with malignancy
• subjects with an acute cardiovascular event within the 3 months before screening for inclusion
• amputee
• pregnancy
• subjects with pacemaker
• subjects with metallic implant