The Impact of Past Coronavirus Disease 19 (COVID-19) Infection on the Live Birth Rates of Frozen Embryo Transfer Cycles

ShangHai Ji Ai Genetics & IVF Institute

Status: Enrolling

Conditions: COVID-19; Frozen Embryo Transfer

Treatments: Other: frozen embryo transfer

Study type: Observational

Funder types: Other

Identifiers

NCT05739019

JIAI 2023-01

Details and patient eligibility

About

This is a prospective observational study. In this study, we aim to investigate the effect of a recent past Covid-19 infection on the live birth rate in the frozen embryo transfer cycles

Enrollment: 1,214 estimated patients

Sex: Female

Ages: 20 to 42 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Women aged 20-42 years at the time of ovarian stimulation for in vitro fertilization
2. Women have embryos frozen prior to COVID infection.

Exclusion criteria

1. Previous COVID infection before oocyte retrieval
2. Recipient of oocyte donation
3. Undergoing preimplantation genetic testing
4. Presence of hydrosalpinx or endometrial polyp which is not surgically treated

Trial design

1,214 participants in 2 patient groups

COVID-19 infection group

Description:

Infertile women attending for frozen embryo transfer with a recent past COVID-19 infection

Treatment:

Other: frozen embryo transfer

Control group

Description:

Infertile women attending for frozen embryo transfer without a recent past COVID-19 infection

Treatment:

Other: frozen embryo transfer