The Impact Of Periodontal Disease Treatment On The General Health Status In Chronic Haemodialyzed Patients (PAROHEM)

A

Anemia Working Group Romania

Status

Unknown

Conditions

Chronic Kidney Disease
Periodontal Disease

Treatments

Other: Dental treatment

Study type

Observational

Funder types

Other

Identifiers

NCT01785355
005
00022 (Registry Identifier)

Details and patient eligibility

About

Several studies revealed a direct relationship between the severity of periodontal inflammation and CRP (NHANES III, Dumitriu HT et al, 1998). In patients without any other source of inflammation but PDD, proper dental treatment of the disease decreased CRP to normal levels (Dumitriu H.T. et al., 1998; D'Aiuto F. et al, 2004; Borawski J. et al., 2007) Moreover, a direct link between high levels of CRP and atherosclerotic complications has been found in studies conducted both in general population (Ridker PM, et al., 1998; Koenig W, et al., 1999) and in HD subjects (Westhuyzen J, et al., 2000; Iseki K., et al., 1999; Zimmermann J, et al. 1998).

Full description

Patients will be recruited according to eligibility criteria. Initial oral and general status will be evaluated and recorded. The evaluated parameters are listed at the study description section. Also, quality of life will be assessed by using the SF-36 and OHIP-14 questionnaires. Patients will undergo a series of dental interventions with the final scope of eliminating all oral inflammation. Participants will also be instructed regarding correct oral hygiene habits. Following dental and periodontal treatments, the oral and general status will be reassessed and the obtained dat analysed.

Enrollment

30 estimated patients

Sex

All

Ages

18 to 85 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Hemodialyzed patients with periodontal disease

Exclusion criteria

  • Malignancies, Diabetes
  • Patient refusal to participate

Trial design

30 participants in 1 patient group

Dental treatment
Description:
Assessment of the clinical state of the patient. Professional prophylaxis and removal of calculus. Extraction of hopeless teeth.Education of patient for oral hygiene. Periodic reevaluation.
Treatment:
Other: Dental treatment

Trial contacts and locations

1

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Central trial contact

Oana Slusanschi, DMD; Liliana Garneata, MD

Data sourced from clinicaltrials.gov

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