The Impact of Preoperative Suggestion on Dreaming

Wonkwang University Hospital

Status: Completed

Conditions: Dream, Day; Ketamine Adverse Reaction; Propofol Adverse Reaction

Treatments: Other: Suggestion Group; Other: Control Group

Study type: Interventional

Funder types: Other

Identifiers

NCT06609538

Wonkwang UH15

Details and patient eligibility

About

Recent studies have shown that positive preoperative suggestions can significantly influence the quality of dreams and reduce the incidence of unpleasant dreams during sedation with agents like ketamine and propofol.

Full description

Cheong et al. demonstrated that a simple positive suggestion before ketamine administration could reduce unpleasant dreams, while Kim et al. found that propofol, compared to midazolam, led to more vivid and memorable dreams, along with similar satisfaction levels in patients. This study aims to extend these findings by comparing the effects of propofol and ketamine sedation on dreaming during anesthesia, with a focus on how preoperative suggestions might influence dream content, emotional tone, and patient satisfaction.

Enrollment: 250 patients

Sex: All

Ages: 20 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Adult patients aged 20-65 years.
• ASA physical status I-III.
• Scheduled for elective spinal anesthesia or brachial plexus block.
• Fluent in Korean.

Exclusion criteria

• Use of any medication, including premedication, within 12 hours before surgery.
• Cognitive impairments or psychiatric disorders (including a history of unpleasant dreams or nightmares).
• Current use of sedatives or hypnotics.
• History of severe or recurrent nightmares.

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: Triple Blind

---

250 participants in 4 patient groups

Control Group with Propofol

Active Comparator group

Description:

Receives standard preoperative instructions and propofol infusion.

Treatment:

Other: Control Group

Suggestion Group with Propofol

Experimental group

Description:

Receives positive preoperative suggestions and propofol infusion.

Treatment:

Other: Suggestion Group

Control Group with Ketamine

Active Comparator group

Description:

Receives standard preoperative instructions and ketamine infusion.

Treatment:

Other: Control Group

Suggestion Group with Ketamine

Experimental group

Description:

Receives positive preoperative suggestions and ketamine infusion.

Treatment:

Other: Suggestion Group