The Impact of Preoperative Supplementation of Zinc

Cairo University (CU)

Status: Completed

Conditions: Nutrition Disorders; Surgery

Treatments: Dietary Supplement: Zinc

Study type: Interventional

Funder types: Other

Identifiers

NCT05785013

MS 277-2022

Details and patient eligibility

About

1. Pre operative anthropometric assessment including : weight in kg, height/length and BMI
2. Pre operative Zinc supplementation (dose according to the age) for 7 days preoperatively for cases
3. Postoperative data collection

Full description

Postoperative data collection :

• Length of hospital stay
• Complication and sorting of them
• Lab withdrawal of inflammatory markers on 2-3 day postoperatively

Enrollment: 1 patient

Sex: All

Ages: 1 month to 12 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. All children patients with Hirschsprung disease admitted for surgical intervention with different ( age , sex )
2. Type of surgery : transanal pull through
3. Whose parents or caregivers approve for the participation in the study

Exclusion criteria

1. Patients with emergency situations
2. Whose parents or caregivers will not apply for the participation in the study

Trial design

Primary purpose: Prevention

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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1 participants in 2 patient groups

Interventional

Experimental group

Description:

25 children diagnosed with Hirschsprung disease and planned for elective surgery will be supplemented with Zinc 7 days before the operation . Outcomes will be evaluated thorugh measuring the hospital length stay. Other parameters including inflammatory markers as CRP , CRP /albumin ratio and development of postoperative complications will be assesed and compared between cases and controls

Treatment:

Dietary Supplement: Zinc

Control

No Intervention group

Description:

25 children diagnosed with Hirschsprung disease and planned for elective surgery will recieve the standard care provided for the cases and will not be supplemented with Zinc . Outcomes will be evaluated thorugh measuring the hospital length. Other parameters including inflammatory markers as CRP , CRP /albumin ratio and development of postoperative complications will be assesed and compared between cases and controls