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The Impact of Protein Intake on Protein Metabolism During Intensified Training

U

University of Toronto

Status

Completed

Conditions

Healthy

Treatments

Dietary Supplement: High
Other: Controlled-diet
Dietary Supplement: Moderate
Dietary Supplement: Normal

Study type

Interventional

Funder types

Other
Industry

Identifiers

Details and patient eligibility

About

Protein requirements in individuals who participate in endurance-based exercise training have been suggested to be greater than the current recommended dietary allowance (RDA).

Our recent study using the minimally invasive indicator amino acid oxidation (IAAO) technique have suggested that protein requirements in young men are at least 30% higher than the recommended protein intake.

The present study will investigate the impact of protein sufficiency on protein metabolism and performance during intensified training periods as a means to further our understanding of the nutritional requirements for the endurance athlete.

Enrollment

12 patients

Sex

Male

Ages

18 to 50 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Healthy, male, endurance-trained participants who have run regularly more than 45 km or 4.5 hours/week
  • Participants who are categorized at least "very good" based on a study by Shvartz & Reibold [40], in which peak rate of oxygen consumption(VO2 Peak) is used as an index. (i.e. the participants whose VO2peak is ≥57 ml/kg/min (18-24 y), ≥54 ml/kg/min (25-29 y), ≥52 ml/kg/min (30-34 y), ≥49 ml/kg/min (35-39 y), ≥47 ml/kg/min (40-44 y), ≥44 ml/kg/min (45-50 y) according to his age,
  • Participants who can cover 10 km in less than 60 min after the VO2peak test and 5 km Time trial on session 2.
  • Participants will be 18-50 years old.
  • Participants are willing to abide by the compliance rules of this study

Exclusion criteria

  • Inability to meet health and physical activity guidelines according to the The Physical Activity Readiness Questionnaire for everyone.
  • Female
  • Inability to adhere to any of the compliance rules judged by principal investigator or medical doctor
  • Regular tobacco use
  • Illicit drug use (e.g. growth hormone, testosterone, etc.)

Trial design

Primary purpose

Basic Science

Allocation

Randomized

Interventional model

Crossover Assignment

Masking

Double Blind

12 participants in 3 patient groups

Normal protein intake
Experimental group
Description:
participants will receive the controlled-diet containing 0.8 g protein /kg/day and the test drink containing 0.14 g protein/kg/d.
Treatment:
Other: Controlled-diet
Dietary Supplement: Normal
Moderate protein intake
Experimental group
Description:
participants will receive the controlled-diet containing 1.20 g protein /kg/day and the test drink containing 0.40 g protein/kg/d.
Treatment:
Other: Controlled-diet
Dietary Supplement: Moderate
High protein intake
Experimental group
Description:
participants will receive the controlled-diet containing 1.83 g protein /kg/day and the test drink containing 1.03 g protein/kg/d.
Treatment:
Other: Controlled-diet
Dietary Supplement: High

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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