The Impact of Riboflavin on the Severity and Duration of Sports Related Concussion

University of Virginia

Status: Completed

Conditions: Sports Related Concussion

Treatments: Drug: Riboflavin 400mg daily

Study type: Interventional

Funder types: Other

Identifiers

NCT02235337

17406

Details and patient eligibility

About

The purpose of this study is to investigate the effectiveness of riboflavin to decrease the duration of time for a student-athlete to return to participation in sports after a sports related concussion.

Enrollment: 248 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All UVa and JMU student-athletes over the age of 18 years old who are diagnosed with a sports related concussion

Exclusion criteria

• Less than 18 years old
• Greater than 24 hours have elapsed since the concussion occurred.
• The student-athlete has already participated in the study during which he/she took Riboflavin
• Non-sports related concussion not incurred while participating in the sport or training for the sport. As an example, a student-athlete who sustains a concussion as a result of a motor vehicle accident will be excluded from the study for that concussion

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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248 participants in 1 patient group

Riboflavin

Experimental group

Treatment:

Drug: Riboflavin 400mg daily