The Impact of Surgical Treatment of Endometriomas on Ovarian Reserve

Saad Amer

Status: Unknown

Conditions: Endometriosis

Treatments: Procedure: Surgery for ovarian endometrioma

Study type: Interventional

Funder types: Other

Identifiers

NCT01425333

R&D: DHRD/2010/089

Details and patient eligibility

About

The aim of this study is to assess which of two commonly used surgical procedures in the treatment of ovarian cysts called endometriomas (cutting out of the cyst - "cystectomy", or draining it and cauterising it's inner lining - "ablation") causes the least damage to the ovary and is therefore best at maintaining the future fertility potential of a patient.

Enrollment: 20 estimated patients

Sex: Female

Ages: 18 to 42 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Women undergoing laparoscopic surgery for treatment of unilateral endometriomas measuring ≥ 3cm and ≤ 8cm in diameter

Exclusion criteria

• Patients who have received oestrogen suppressing drugs (e.g. oral contraceptive pills, GnRHa) during the previous six months
• Patients who have previously undergone surgical treatment of endometriomas
• Patients with bilateral endometriomas
• Patients with endometriomas of less than 3cm in size or more than 8cm in size
• Pre-surgical evidence of reduced ovarian reserve
• Pregnant patients
• Patients unable to give informed consent e.g. patients with mental incapacity

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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20 participants in 2 patient groups

Cystectomy

Active Comparator group

Description:

Patients undergoing cystectomy for ovarian endometrioma

Treatment:

Procedure: Surgery for ovarian endometrioma

Procedure: Surgery for ovarian endometrioma

Ablation

Active Comparator group

Description:

Patients undergoing ablation for ovarian endometrioma

Treatment:

Procedure: Surgery for ovarian endometrioma

Procedure: Surgery for ovarian endometrioma