The Impact of the Adequacy of Keratinized Mucosa on Peri-implant Tissue Health and Patient-reported Outcomes

The Dental Hospital of Zhejiang University School of Medicine

Status: Enrolling

Conditions: Edentulous Alveolar Ridge

Treatments: Other: No intervention

Study type: Observational

Funder types: Other

Identifiers

NCT07124416

2025-104

Details and patient eligibility

About

This study aims to conduct a cross-sectional study to compare the differences in clinical indices, patient-reported outcomes, and levels of inflammatory factors in peri-implant gingival crevicular fluid between sites with adequate (≥ 2 mm) and inadequate (< 2 mm) keratinized mucosa after implant restoration, in order to explore the impact of the presence of keratinized mucosa on peri-implant soft and hard tissue health.

Enrollment: 150 estimated patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Individuals aged 18 to 70 years (inclusive of 18 and 70 years), of any gender;
• Patients who have undergone dental implant restoration是（single crown or fixed bridge restorations） at the Stomatology Hospital, Zhejiang University School of medicine and have had their final restoration for at least 6 months;
• Patients who voluntarily participate and sign the informed consent form after being fully informed, and who cooperate with relevant examinations.

Exclusion criteria

• Patients who are unwilling to participate in the follow-up of this study for various reasons

Trial design

150 participants in 2 patient groups

inadequate keratinized mucosa

Description:

peri-implant width of keratinized mucosa less than 2 mm

adequate keratinized mucosa

Description:

peri-implant width of keratinized mucosa ≥ 2 mm

Treatment:

Other: No intervention