The Impact of the Glycaemic Index (GI) on Daily Blood Glucose Profiles and Food Intake in Young Chinese Adult Males

Clinical Nutrition Research Centre, Singapore

Status: Completed

Conditions: Prediabetes; Obesity; Type 2 Diabetes

Treatments: Other: Rice and bread (low GI); Other: Rice and bread (high GI)

Study type: Interventional

Funder types: Other

Identifiers

NCT02340507

2013/00266

Details and patient eligibility

About

This study is carried out to find out the inclusion of high and low glycaemic Index (GI) foods to daily meals impact on 24 hour blood glucose fluctuations and food intake.

Full description

The GI is a method of classifying foods based on the food's ability to raise the blood glucose level. Low GI foods are recommended as they have a lower impact on blood glucose concentrations and also reduce total food intake. There is very little information on how eating high and low GI foods affect daily blood glucose concentrations in Asians. Therefore, the objective of this study is to observe the effect of eating high and low GI breakfasts and snacks on 24 hour blood glucose concentrations and food consumption in Asian males. Healthy, normal-weight, Chinese males will be recruited. There will be two sessions (consisting of four days for each session) where they will consume either a high or low GI breakfast or snack, and a standardized ad libitum lunch buffet. Their glycaemic response will be measured using a Continuous Glucose Monitoring System (CGMS) throughout the period. The proposed research for the first time demonstrates how the consumption of high and low GI breakfasts and snacks affect subsequent energy intake and 24 hour blood glucose profiles in Asians. These findings will have significant public health benefits for optimum weight and dietary control.

Enrollment: 15 patients

Sex: Male

Ages: 21 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Chinese, male
• Age between 21-40 years
• Body mass index between 17 to 24 kg/m2
• Normal blood pressure (120/80 Hgmm)
• Fasting blood glucose < 6 mmol/L

Exclusion criteria

• Having any metabolic diseases (such as diabetes, hypertension etc)
• One prescription medication
• Partaking in sports at the competitive and/or endurance levels
• Allergic/intolerant to any of the test foods
• Intentionally restricting food intake
• Smoking

Trial design

15 participants in 2 patient groups

High glycemic index

Experimental group

Description:

The subject will consume a high glycemic index glutinous rice for breakfast (75g available carbohydrates), and a high glycemic index white bread for snack (25g available carbohydrates). The lunch is a standardized, weighed portion buffet.

Treatment:

Other: Rice and bread (high GI)

Low glycemic index

Experimental group

Description:

The subject will consume a low glycemic index parboiled basmati rice for breakfast (75g available carbohydrates), and a low glycemic index multigrain bread for snack (25g available carbohydrates). The lunch is a standardized, weighed portion buffet.

Treatment:

Other: Rice and bread (low GI)