The Impact of the Timing of Trigger on IVF Success

Colorado Center for Reproductive Medicine

Status: Terminated

Conditions: Fertilization in Vitro; Infertility; Embryonic Development

Treatments: Other: Timing of trigger

Study type: Interventional

Funder types: Other

Identifiers

NCT02990949

20160397

Details and patient eligibility

About

The aim of this study is to examine the length of ovarian stimulation with the timing of trigger in an IVF cycle and its potential to impact patient outcomes.

Enrollment: 29 patients

Sex: Female

Ages: 26 to 44 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Planning to move forward with an IVF cycle
• Have met the requirements of being a patient at CCRM Colorado
• AMA: 39-44 years old And/or
• DOR: AMH < 1 & FSH >10 (age independent)

Exclusion criteria

• Contraindication for pregnancy
• Have not fulfilled requirements for IVF cycle
• Single gene couple or chromosomal rearrangement
• Severe male factor or testicular surgical sperm removal (need sufficient sperm for ICSI)
• One ovary
• Uterine anomalies
• Stage III or IV endometriosis
• Explained recurrent miscarriage
• PCO or PCOS
• Using donor oocyte or gestational carrier

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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29 participants in 2 patient groups

Testing group

Experimental group

Description:

Timing of trigger at end of ovarian stimulation in an IVF cycle: trigger when 2 follicles reach 18mm, OR 1 follicle reaches 18mm AND 1 follicle is between 16-18mm.

Treatment:

Other: Timing of trigger

Control group

No Intervention group