The Impact of Two-field or Three-field Lymphadenectomy on Overall Survival in Middle and Lower Thoracic Esophageal Squamous Cell Carcinoma: An Observational Study

Yongtao Han

Status: Completed

Conditions: Esophageal Cancer

Treatments: Diagnostic Test: Since the data were collected retrospectively, there were no interventions

Study type: Observational

Funder types: Other

Identifiers

NCT05617352

SCCH-TS2204

Details and patient eligibility

About

To clarify the effect of Two-field or Three-field Lymphadenectomy on the survival of esophageal squamous cell carcinoma.

Enrollment: 1,659 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 1. Men and women aged 18-85 years
• 2. Histologically confirmed primary thoracic esophageal squamous cell carcinoma,
• 3. Staging PT1b-4A, N0-3, M0 AJCC eighth edition
• 4. Excluding lymph node dissection < 15, (meeting the guideline criteria)
• 5. The tumor located in the lower middle thoracic.

Exclusion criteria

• 1. Patients with a history of previous thoracic and abdominal surgery that may affect lymphatic reflux
• 2. Patients with distant metastasis confirmed by imaging
• 3. Patients with obvious surgical contraindications.

Trial design

1,659 participants in 2 patient groups

2F Group

Description:

Patients with Two-field Lymphadenectomy

Treatment:

Diagnostic Test: Since the data were collected retrospectively, there were no interventions

3F Group

Description:

Patients with Three-field Lymphadenectomy

Treatment:

Diagnostic Test: Since the data were collected retrospectively, there were no interventions