The Impacts of the Different Anesthesia Methods on Patients of Transbronchial Cryobiopsy

Guangzhou Institute of Respiratory Disease

Status: Unknown

Conditions: Tracheal Intubation; Transbronchial Cryobiopsy; Rigid Bronchoscopy; Safety; Anesthesia

Treatments: Procedure: anesthesia

Study type: Interventional

Funder types: Other

Identifiers

NCT04099069

TS20180110

Details and patient eligibility

About

to evaluate the difference between the tracheal intubation (TI) and rigid bronchoscopy (RB) under general anesthesia on patients with transbronchial cryobiopsy.

Full description

To evaluate the difference between the tracheal intubation (TI) and rigid bronchoscopy (RB) under general anesthesia on patients with transbronchial cryobiopsy. Comparing the difference between two groups in the operating duration, extubation duration, total anesthesia time, heart rate, blood pressure and arterial blood gas analysis. This is a prospective, randomized, controlled trial.

Enrollment: 60 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. The patients are admitted in the institution as ILD, while undefined after thorough history collection, laboratory examination and radiological data.
2. Transbronchial cryobiopsy(TBCB) is indicated by clinicians for definitive diagnosis and patients are content with the examination with agreement signed.
3. Blood gas analysis, routine blood test, ECG examination, coagulation function, immunological examination, chest HRCT, and liver/kidney function test have been completed

Exclusion criteria

1. The radiological data indicates non-ILD
2. The clinical examinations mentioned above are not completed.
3. The patient cannot endure or does not agree the procedure.

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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60 participants in 2 patient groups, including a placebo group

trachial intubation

Placebo Comparator group

Description:

patient was insert trachial intubation with normal frequency jet ventilation

Treatment:

Procedure: anesthesia

rigid bronchoscopy

Experimental group

Description:

patient was insert trachial intubation with high frequency jet ventilation

Treatment:

Procedure: anesthesia