The Incidence and the Risk Factors of Nephrocalcinosis in Very Preterm Infants

Vilnius University

Status: Completed

Conditions: Nephrocalcinosis; Preterm Infant

Study type: Observational

Funder types: Other

Identifiers

NCT04382976

158200-R-100

Details and patient eligibility

About

The study aims to assess the incidence and the risk factors of nephrocalcinosis in very preterm infants using patient data collected during hospitalisation at the Neonatology Centre.

Full description

Nephrocalcinosis in preterm infants develops as a result of imbalance between the factors promoting or inhibiting formation of kidney stones. It is caused by intensive treatment as well as functional and morphological kidney immaturity. There is a correlation between the prevalence of nephrocalcinosis and low gestational age.

The study aims prospectively to assess the incidence and the risk factors of nephrocalcinosis in very preterm infants less than 32 weeks of gestation.

Enrollment: 171 patients

Sex: All

Ages: 23 to 31 weeks old

Volunteers: No Healthy Volunteers

Inclusion criteria

• preterm infants of the gestational age of <32 weeks;
• parental consent acquired.

Exclusion criteria

• death before 28 days of age;
• congenital defects;
• no kidney ultrasound results;
• no parental consent.