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The Incidence and Treatment of Insulin Resistance Among Men With Erectile Dysfunction

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Penn State Health

Status

Completed

Conditions

Erectile Dysfunction
Insulin Resistance
Metabolic Syndrome

Study type

Observational

Funder types

Other

Identifiers

NCT00284960
NIH: K24 H001476
18805

Details and patient eligibility

About

Determine if men with erectile dysfunction (ED) are more likely to have insulin resistance compared to healthy controls.

Full description

Insulin is a hormone produced by the body that lets sugar into the cells, where it is used for energy. Insulin resistance occurs when the body's cells have a decreased ability to react to insulin. This leads to an increase in insulin secretion. Over time, insulin resistance can lead to higher levels of sugar in the blood (diabetes), and can also contribute to obesity, high blood pressure, high cholesterol levels and heart disease. There are no simple tests to actually diagnose insulin resistance. Currently, the glucose tolerance test is used to diagnose IR, but it involves several blood draws over a 2-hour period. Another purpose of this study is to compare a blood test involving only one blood draw to the 2-hour glucose tolerance test, which involves several blood draws over a 2-hour period.

It is well known that diabetes often leads to erectile dysfunction. Because insulin resistance occurs before diabetes, it is possible that erectile dysfunction may occur in some individuals while they have insulin resistance, but before they develop diabetes. If this is true, it might be possible to use erectile dysfunction as a sign of insulin resistance, which may lead to more timely treatment of insulin resistance and may delay or prevent the development of diabetes, and the other problems mentioned above.

Sex

Male

Ages

18 to 65 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • 18-65 years of age, male,

Exclusion criteria

  • diabetes, peyronies

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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