The Inflammatory Burden in Hemodialysis vs. Peritoneal Dialysis Patients: the Role of Alpha-defensin

Hillel Yaffe Medical Center

Status: Unknown

Conditions: Kidney Failure; Inflammation

Treatments: Diagnostic Test: Blood Test

Study type: Interventional

Funder types: Other

Identifiers

NCT03845530

HYMC-123-18

Details and patient eligibility

About

The aim of this study is to determine the levels of alpha-defensin throughout the hemodialysis course compared to the levels at the end of a course of peritoneal dialysis, as a reflection of the inflammatory burden.

Enrollment: 80 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Kidney failure patients undergoing hemodialysis or peritoneal dialysis

Exclusion criteria

• Active inflammatory or infectious disease

Trial design

Primary purpose: Prevention

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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80 participants in 2 patient groups

Hemodialysis group

Active Comparator group

Description:

Blood sample taken and sent to laboratory for analysis

Treatment:

Diagnostic Test: Blood Test

Peritoneal dialysis

Active Comparator group

Description:

Blood sample taken and sent to laboratory for analysis

Treatment:

Diagnostic Test: Blood Test