The Influence of an Acute Exacerbation During Pulmonary Rehabilitation in COPD Patients Awaiting Lung Transplantation

Klaus Kenn

Status: Completed

Conditions: Chronic Obstructive Pulmonary Disease

Treatments: Other: Pulmonary Rehabilitation

Study type: Observational

Funder types: Other

Identifiers

NCT04363723

AECOPD pre-LTX

Details and patient eligibility

About

Data from chronic obstructive pulmonary disease patients awaiting lung transplantation which performed a pulmonary rehabilitation program will be analyzed retrospectively. Acute exacerbations occur frequently in these patients and have a major impact on the course of the disease. This study investigates the prevalence and the impact of acute exacerbations during pulmonary Rehabilitation in patients with severe chronic obstructive pulmonary disease patients awaiting lung Transplantation that continued the Rehabilitation program despite an acute exacerbation. Data will be taken from the internal database of the reference center (Schoen Klinik Berchtesgadener Land, Schoenau, Germany) where these data were collected during clinical routine.

Enrollment: 559 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• confirmed diagnosis of chronic obstructive pulmonary disease including patients with alpha-1 antitrypsin deficiency
• listed for lung Transplantation or in the Evaluation process for lung transplantation
• performed a pulmonary rehabilitation program at the reference center

Exclusion criteria

• patients that discontinued the pulmonary Rehabilitation program due to any reason and could therefore not perform assessement tests at the end of regular Rehabilitation program

Trial design

559 participants in 2 patient groups

patients with an acute exacerbation during Rehabilitation

Description:

Patients with severe chronic obstructive pulmonary disease awaiting lung Transplantation that developed an acute exacerbation during a pulmonary Rehabilitation program but continued the Rehabilitation program

Treatment:

Other: Pulmonary Rehabilitation

patients without an acute exacerbation during Rehabilitation

Description:

Patients with severe chronic obstructive pulmonary disease awaiting lung Transplantation that did not develop an acute exacerbation during a pulmonary Rehabilitation program and completed the Rehabilitation program regularly.

Treatment:

Other: Pulmonary Rehabilitation