The Influence of Baseline Sensitivity and Expectation on Exercise-induced Hypoalgesia in Young Healthy Adults

Marquette University

Status: Unknown

Conditions: Healthy Subjects

Treatments: Other: Submaximal isometric exercise

Study type: Interventional

Funder types: Other

Identifiers

NCT03871504

HR-2999

Details and patient eligibility

About

The purpose of this study is to investigate the influence of baseline experimental pain sensitivity and expectation on the pain response following a single exercise session. Pain assessment will be done with different intensities of noxious stimuli. In addition, the expectation of how exercise impacts pain will be studied.

Full description

The relation between baseline pain sensitivity and the pain response following exercise is not clear. The aims of this study are to investigate the influence of baseline experimental pain sensitivity on the pain response following submaximal isometric exercise, and whether expectations would influence outcomes with subsequent exposure to exercise.

Enrollment: 250 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy adults
• English proficiency

Exclusion criteria

• Acute pain condition
• Chronic pain condition
• Mental health disorder
• Cardiovascular disease
• Any chronic illness
• Difficulty with physical exercise
• Recent surgery
• Pulmonary disease
• Diabetes
• Smoking
• Raynaud disease
• Claustrophobia

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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250 participants in 2 patient groups

submaximal isometric exercise.

Experimental group

Description:

submaximal isometric exercise will be performed.

Treatment:

Other: Submaximal isometric exercise

Quiet rest.

No Intervention group

Description:

Subject will rest in seating position for a period that mimics the exercise time.