The Influence of Chlorella Supplementation on Running Performance

University College London (UCL)

Status: Enrolling

Conditions: Healthy; Athletes

Treatments: Dietary Supplement: Placebo supplementation; Dietary Supplement: Chlorella supplementation

Study type: Interventional

Funder types: Other

Identifiers

NCT06479993

21745/002.1

Details and patient eligibility

About

Algae, such as chlorella, are gaining popularity as a nutritious additive to whole food or as a supplement. They contain a variety of beneficial nutrients like vitamins, minerals, healthy fats, and amino acids, which can have positive effects on our health and possibly athletic performance. Chlorella, specifically, is a type of single-celled green algae that you can easily find in health stores worldwide. While there's some evidence suggesting that chlorella supplementation might improve submaximal and maximal performance for cyclists, it's unclear if it has the same impact on runners. To investigate this, the investigators aim to conduct a double-blind randomised placebo controlled study to see if taking chlorella daily for 3-weeks can enhance different aspects of running performance, both during low/moderate and intense exercise, among individuals who regularly engage in running.

Full description

After signing the consent form, we will invite you to come to the ISEH laboratory on Tottenham Court Road so we can take some basic baseline readings. This should last up to 60 minutes and will also include a V̇o2max Test (visit 1). After this, you will be randomly allocated either start on chlorella or placebo first. After supplementation (for visit 2 and 3) you will be required to perform a submaximal running test which will entail running at 60% GET (gas exchange threshold), 80% GET, and 75% of the change from peak. This will then be shortly followed by an incremental test to fatigue.

You will then be required to undergo the exact same supplementation period on the alternative supplement with the same exercise test performed.

You will be required to come into the laboratory a total of 3 times. Each visit should take roughly 1 - 1.5 hours.

Enrollment: 20 estimated patients

Sex: All

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Aged 18-50.
• Run regularly (3-4 times a week).
• Train with a purpose to compete.
• Consider running to be your main sport.
• Be comfortable running continuously for over 30-minutes at moderate intensity.
• Represent a local running club.

Exclusion criteria

• Individuals taking blood thinners.
• Known allergies to algae/mould and iodine.
• Any illness/conditions identified on PARQ (please see attached PARQ)
• Taking immunosuppressant medication

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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20 participants in 2 patient groups, including a placebo group

Chlorella supplementation

Experimental group

Description:

Supplementation of chlorella (6g/day for 3-weeks)

Treatment:

Dietary Supplement: Chlorella supplementation

Placebo supplementation

Placebo Comparator group

Description:

Supplementation of placebo (6g/day for 3-weeks)

Treatment:

Dietary Supplement: Placebo supplementation