The Influence of Different At-home Exercise Strategies on 24h Glycemic Control

University of Toronto

Status: Completed

Conditions: Metabolic Disturbance

Treatments: Behavioral: Bodyweight interval exercise; Behavioral: Walking

Study type: Interventional

Funder types: Other

Identifiers

NCT05490706

42756-2

Details and patient eligibility

About

This study will determine how different at-home exercise strategies influence 24hr glycemic control in women with metabolic dysfunction.

Full description

Elevations in blood glucose concentration increase risk for cardiometabolic diseases including type 2 diabetes and cardiovascular diseases. Exercise can improve glycemic control, but there is limited research comparing the effectiveness of different exercise strategies in women. The aim of this study is to examine, under free-living conditions, how performing either walking and bodyweight interval exercise after dinner influences glycemic control in women with or at risk for type 2 diabetes. Glycemic control will be measured with continuous glucose monitors.

Enrollment: 107 patients

Sex: Female

Ages: 50+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Females
• no cancer history
• ≥50 years old
• Have metabolic dysfunction (defined as self-reported diagnosis of pre-diabetes, type 2 diabetes, or at least moderate Canadian diabetes risk (CANRISK) score)
• Owns a smartphone with Bluetooth capability with Apple or Android operating system
• deemed safe to exercise as per the CSEP Get Active Questionnaire
• Enrolled in NCT05454943

Exclusion criteria

• Type 1 diabetes
• Taking exogenous insulin, sulfonylureas, or GLP-1 receptor agonists
• Self-reported history of an eating disorder
• BMI <18.5 kg/m
• Working night or rotating shifts
• Eating window <12 hours or consistently eating less than 3 meals/day in the past 3 months
• Major dietary changes within the past 3 months (i.e. calorie counting, ketogenic diet)

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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107 participants in 3 patient groups

Bodyweight interval exercise

Experimental group

Description:

Performing 15 minutes of bodyweight interval exercise after dinner

Treatment:

Behavioral: Bodyweight interval exercise

Walking

Experimental group

Description:

Performing a 30 minute walk after dinner

Treatment:

Behavioral: Walking

Non exercise control

No Intervention group

Description:

Performing no exercise after dinner