the Influence of General Anesthesia on Tumor Metastasis and Recurrence

Shanghai Jiao Tong University

Status: Unknown

Conditions: Tumor Recurrence and Metastasis

Treatments: Other: general anesthesia and local anesthesia

Study type: Observational

Funder types: Other

Identifiers

NCT02474511

仁济伦审[2015]058K

Details and patient eligibility

About

The purpose of this study was to investigate whether general anesthesia will affect the postoperative recurrence and metastasis of malignant tumor.

Enrollment: 300 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ASA I - III Primary liver cancer tumor is single and diameter is less than 3 centimeter There is no major vascular invasion phenomenon, no lymph nodes or extrahepatic metastases The Child - Pugh belong to type A or type B

Exclusion criteria

• Had a history of liver surgery (including radiofrequency ablation) Severe disease of heart, lung, kidney, the immune system INR > 1.5 or platelet count is less than 45000 cells/mm3 History of opioid addiction Metastatic liver tumors Not sure of primary liver cancer Don't agree to participate in this experiment

Trial design

300 participants in 2 patient groups

general anesthesia

Description:

In this group，the patient is received radiofrequency ablation under general anesthesia.

Treatment:

Other: general anesthesia and local anesthesia

local anesthesia

Description:

In this group，the patient is received radiofrequency ablation under local anesthesia.

Treatment:

Other: general anesthesia and local anesthesia