The Influence of Lidocaine Volume on Discomfort During Administration of Local Anesthetic

Norwegian University of Science and Technology

Status: Completed

Conditions: Needlestick Injuries

Treatments: Procedure: 2 ml 1% Lidocaine; Procedure: 1 ml 2% Lidocaine

Study type: Interventional

Funder types: Other

Identifiers

NCT02086292

2013/2297D

Details and patient eligibility

About

The aim of the study is to find a simple method for pain reduction that can be used in clinical practice when administering digital nerve block with a single subcutaneous injection. It will be investigated whether a smaller volume of lidocaine can decrease pain during injection.

Full description

Healthy volunteers will receive a single subcutaneous injection digital nerve block at the base of each ring finger. 2ml 1% lidocaine in one of the fingers, and 1 ml 2% lidocaine in the other. After each injection, the subject will be asked to evaluate the pain on a visual analog scale (0-100 mm). Additionally the sensibility will be tested with a Semmes-Weinstein monofilament, to evaluate if the different methods achieve desired anesthetic effect.

Enrollment: 36 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• age 18 - 65

Exclusion criteria

• regular use of analgesics
• known hypersensitivity of local anaesthetic
• renal-, heart- or liver disease
• known peripheral neuropathy or diabetes mellitus
• local infection on injection site
• circulation disorders in upper extremities (e.g. Raynaud´s phenomenon)

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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36 participants in 2 patient groups

2 milliliter lidocaine

Experimental group

Description:

2 ml 1% Lidocaine in one ring finger, 1 ml 2% Lidocaine in the other ring finger

Treatment:

Procedure: 2 ml 1% Lidocaine

1 milliliter lidocaine

Experimental group

Description:

1 ml 1% Lidocaine in one ring finger, 2 ml 2% Lidocaine in the other ring finger

Treatment:

Procedure: 1 ml 2% Lidocaine