The Influence of Oral Hygiene on Local Wound and Systemic Infection in Patients With Percutaneous Endoscopic Gastrostomy Placement (PEG)

Hillel Yaffe Medical Center

Status and phase: Unknown; Phase 3

Conditions: Dysphagia; Peristomal Wound Infection

Treatments: Drug: Chlorhexidine gluconate 0.2%; Other: Plain water

Study type: Interventional

Funder types: Other

Identifiers

NCT00859235

HY022009

Details and patient eligibility

About

Percutaneous endoscopic gastrostomy (PEG) is commonly used for long term enteral feeding of patients with severe dysphagia. The most common complication is peristomal wound infection. The possible mechanism the bacterial from the oral cavity disseminate during the PEG insertion through the stomach to the abdominal wall, in spite the routine use of antibiotic prophylaxis, have reported low rates of wound infection in patients who were already receiving antibiotics at the time of PEG Our hypothesis that washing the oral cavity with antibiotic solution prior the insertion PEG , We planned a prospective, randomised, double blind, one centre study of antibiotic mouth wash solution (0.2% Chlorhexidine gluconate) as.prophylaxis in PEG

Enrollment: 50 estimated patients

Sex: All

Ages: 45 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All patients scheduled to undergo PEG

Exclusion criteria

• Previous GI surgery
• Coagulopathy
• Sepsis

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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50 participants in 2 patient groups, including a placebo group

1

Active Comparator group

Treatment:

Drug: Chlorhexidine gluconate 0.2%

2. Plain water

Placebo Comparator group

Treatment:

Other: Plain water