The Influence of Placental Drainage of Management of the Third Stage of Labor:a Randomized Controlled Study

Istanbul Bakirkoy Maternity and Children Diseases Hospital

Status: Completed

Conditions: Postpartum Haemorrhage

Treatments: Behavioral: Placental cord drainage

Study type: Interventional

Funder types: Other

Identifiers

NCT01931423

Aşıcıoğlu-06

Details and patient eligibility

About

To determine whether early placental drainage plus cord traction reduces the incidences of manual removal and blood loss, and to determine the risk factors associated with blood loss after delivery.

Enrollment: 485 patients

Sex: Female

Ages: 18 to 44 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. greater than 37 gestational weeks
2. single pregnancy
3. vaginal delivery
4. estimated fetal weight 2500-4500 gr.

Exclusion criteria

1. PPROM
2. 37 or lower gestational week
3. multiple pregnancy
4. grand multiparıty (greater than 5)
5. coagulation defects (HELLP, ablation placenta, previa, pre-eclampsia)
6. a history of any bleeding during pregnancy
7. caesarean delivery or any uterine scar
8. a history of postpartum haemorrhage
9. hydramnios
10. known uterine anomalies
11. suspected abnormal placentation (accreta, increta, or percreta)
12. prepartum hemoglobin concentration less than 8 g/dL
13. history of anticoagulant drugs and prolongation of the first stage of labor longer than 15 hours

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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485 participants in 2 patient groups, including a placebo group

Drainage Group

Placebo Comparator group

Description:

early placental drainage plus cord traction

Treatment:

Behavioral: Placental cord drainage

Controlled Group

No Intervention group

Description:

spontaneous removal placenta