The Influence of Psychological Interventions Upon Disease Progression in HIV-infected Patients Receiving no Medication

Imperial College London

Status: Completed

Conditions: HIV Infected Individuals

Treatments: Behavioral: Hypnosis

Study type: Interventional

Funder types: Other

Identifiers

NCT00180700

Johrei_HIV1

Details and patient eligibility

About

This study examines the hypothesis that psychological interventions have beneficial effects on quality of life including psychological well-being and disease progression in early HIV patients recieving no medication.

Full description

Hypothesis: This investigation is based upon the hypothesis that psychological intervention may counteract the detrimental effects of stress both on psychological well-being and on general health.

Background: HIV infection may be considered to be a life-long biological and psychological stressor leading to detrimental outcomes associated with disease progression. Stress reduction in these patients may have beneficial effects through delaying disease progression via the proposed interactive psycho-neuro-endocrine-immune network.

Inclusion Criteria:

HIV infected individuals CD4 T-cell counts above 200 cells/mcl Receiving no anti-retroviral drugs Individuals who signed the informed consent form

Investigative approach: Self-hypnosis and a Japanese non-touching, laying-on-of hands-like technique, called Johrei, were used to investigate the effects of psychological intervention upon immune parameters (especially in CD4 counts) associated with disease progression along with phenomenological associations between stress perception and stress hormone levels in HIV-infected patients receiving no medication.

Enrollment: 22 patients

Sex: All

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• HIV infected
• CD4 T-cell counts above 200 cells/mcl
• Signed the informed consent form

Exclusion criteria

• receiving anti-retroviral drugs

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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22 participants in 2 patient groups

Self-hypnosis

Experimental group

Description:

A course of four weekly 2-hour training sessions coupled with daily self-hypnosis practice was given to 13 participants with diagnosed HIV

Treatment:

Behavioral: Hypnosis

Johrei healing method

Experimental group

Description:

A course of four weekly 2-hour training sessions coupled with daily self-hypnosis practice was given to 9 participants with diagnosed HIV

Treatment:

Behavioral: Hypnosis