The Influence of Testosterone on Experimental Pain Perception

University of New Mexico (UNM)

Status and phase

Completed

Early Phase 1

Conditions

Acute Pain

Treatments

Other: Placebo Syrup

Drug: Testosterone

Study type

Interventional

Funder types

Other

Identifiers

NCT05781685

1100595-3

Details and patient eligibility

About

This trial examined how the administration of exogenous testosterone would influence pain tolerance and other endogenous steroids (i.e. estradiol and progesterone).

Enrollment

20 patients

Sex

Female

Ages

18 to 25 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Healthy college-aged females that are over the age of 18 and younger than 25 will be used for this study.

Exclusion criteria

The following criteria will exclude a participant from the study:
Anyone that has a tree nut allergy.
Women that are pregnant or may feel that they may be pregnant or breast-feeding.
Anyone taking supplements that may influence their testosterone level.
Anyone taking any kind of steroid that may increase their testosterone level.
Anyone that smokes tobacco or uses smokeless tobacco.
Anyone that reports any condition associated with nerve damage.
Anyone that is using hormonal contraceptive.
Anyone who was sick or unwell at the time of screening.
Each participant completed a Testosterone Pre-Screen form. This form asked each participant individually whether they are taking any drugs or have any conditions that might be exacerbated by testosterone. This form was completed before they signed the consent form and each time they arrived in the lab for an experimental session.