The Influences of Malnutrition and Inflammation Complex Syndrome in Hemodialysis Patients

Far Eastern Memorial Hospital

Status: Unknown

Conditions: Cerebrovascular Accident; Inflammation; Hemodialysis; Myocardial Ischemia; Malnutrition

Study type: Observational

Funder types: Other

Identifiers

NCT00190125

FEMH-94008

Details and patient eligibility

About

The purpose of this study is to explore the severity of malnutrition and inflammation in Taiwanese hemodialysis patients.

Full description

Cardiovascular disease is the major of cause of mortality of hemodialysis patients. In addition to diabetes and hypertension, malnutrition and chronic inflammation are well-known to be major risk factors of cardiovascular diseases in normal population. For detecting the malnutrition and chronic inflammation and understanding the exact influences to hemodialysis patients, we conduct this study. We will collect the biochemical parameters, inflammatory markers, lipid parameters, hematologic parameters, and genomic DNA of patients. Then we will prospectively record the hospitalization, cardiovascular events, complications of arteriovenous fistula/graft, and mortality. According to the above results, we try to explore the exact role of malnutrition and inflammation in hemodialysis patients.

Enrollment: 300 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients who have received hemodialysis therapy for more than three months

Exclusion criteria

• Having active infection diseases now
• Patients who have a malignancy
• Had cardiovascular events in recent three months