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The Interaction Between Resting Metabolic Rate, Physical Activity and Thyroid Hormone in Females

S

Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences

Status

Completed

Conditions

Resting Energy Expenditure
Thyroid
Physical Activities

Study type

Observational

Funder types

Other

Identifiers

NCT06377943
SIAT-IRB-240415-H0718

Details and patient eligibility

About

This Study is focused on the interaction between resting metabolic rate (RMR), physical activity (PA), and thyroid hormones (TH). TH controls almost all the cell activities of the body so, it is known as one of the major regulatory hormones. This is the reason for individuals who suffer from thyroid disorders show abnormal metabolism. Recently it was suggested that interindividual variations in thyroid hormone levels also influence daily physical activity.

Full description

In this study, investigators will recruit adult females with a BMI ≥18.5. After the screening process, eligible volunteers will undergo certain measurements including body composition, resting metabolism daily physical activity, thyroid hormone levels, and total energy expenditure. The investigators will access the changes in resting metabolism and daily physical activities with the differences in thyroid hormone levels.

Enrollment

42 patients

Sex

Female

Ages

18 to 50 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Female age ≥18;
  • BMI≥18.5

Exclusion criteria

  • Intended weight change exceeding 2kg within the past three months;
  • Having any special medical diets or having eating disorders;
  • Pregnant women or breastfeeding women;
  • People who have metal implants in their bodies;
  • Patients with metabolic diseases, infectious diseases, and genetic disorders such as hypothyroidism, and hyperthyroidism;
  • Patients with a personal or family history of medullary thyroid carcinoma (MTC), or patients with rare type 2 multiple endocrine tumor syndrome (MEN2); People with a fear of needles (Trypanophobia), claustrophobia; People who are fear of blood (Hemophobia) or pathological hypotension;

Trial contacts and locations

1

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Central trial contact

Sanduni S De Alwis, Bachelor; John R Speakman, PhD

Data sourced from clinicaltrials.gov

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