The Interactive Physical and Cognitive Exercise System (iPACES™)

Union College, New York

Status: Unknown

Conditions: MCI; Aging; Cognitive Change; Cognitive Impairment; Neurocognitive Disorder; Mild Cognitive Impairment; Alzheimer Disease, Early Onset

Treatments: Device: interactive Physical and Cognitive Exercise (iPACES™); Behavioral: physical exercise alone (PES) first; Device: cognitive exercise alone (iCE) first

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT03069391

16028

1R41AG053120-01 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

This study is intended to clarify the benefits to brain health and thinking processes that result from different forms of exercise. In particular, this study will investigate the possible benefits of physical exercise (such as pedaling an under-table stationary elliptical) or mental exercise (such as playing a videogame on a portable tablet), or combining these activities together (as in the iPACES™ exergame).

Enrollment: 31 patients

Sex: All

Ages: 50+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• co-residing older adults (e.g., spouses, partners, roommates, relatives)
• both at least 50 years of age
• normative/typical cognitive function or those with Mild Cognitive Impairment (MCI) or mild Neurocognitive Disorder (mNCD) or early Alzheimer's disease
• adequate vision and dexterity for on-screen assessments
• able to pedal an under-table elliptical
• permission of primary care provider and cardiologist (if applicable)

Exclusion criteria

• history of seizure
• Parkinson's disease
• significant dementia/memory loss

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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31 participants in 2 patient groups

physical, cognitive, then interactive

Active Comparator group

Description:

physical exercise alone (PES) first, then iPACES

Treatment:

Behavioral: physical exercise alone (PES) first

Device: interactive Physical and Cognitive Exercise (iPACES™)

cognitive, physical, then interactive

Active Comparator group

Description:

cognitive exercise alone (iCE) first, then iPACES

Treatment:

Device: cognitive exercise alone (iCE) first

Device: interactive Physical and Cognitive Exercise (iPACES™)