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The Intraoperative Physiologic Changes of Patients Under Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Cytoreductive Surgery; Prospective Observational Study

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Yonsei University

Status

Completed

Conditions

Peritoneal Surface Malignancies

Treatments

Drug: HIPEC cytoreductive surgery

Study type

Observational

Funder types

Other

Identifiers

NCT02325648
4-2014-0854

Details and patient eligibility

About

The most popular surgical treatment of peritoneal cancer is the type known as hyperthermic intraperitoneal chemoperfusion (HIPEC), a type of cytoreductive surgery for which a significantly high survival rate has been demonstrated by several studies. It is widely known that HIPEC entails severe physiological changes and precautions during anesthesia. However, very few studies have systematically outlined and organized these changes for each system, and most existing studies only report retrospective data or are limited to gynecological surgeries. Therefore, the present researchers planned a prospective observational study to determine the physiological changes that occur in patients during HIPEC cytoreductive surgeries performed in the colon and rectal surgery department of the investigators hospital. The investigators planned to monitor the patients' body temperature, metabolism, cardiovascular and respiratory changes during HIPEC cytoreductive surgery and analyze the anesthetic methods applied to identify the optimal anesthetic management strategy for HIPEC cytoreductive surgeries.

Enrollment

22 patients

Sex

All

Ages

20+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Adult patients 20 years of age or older who will undergo HIPEC cytoreductive surgery at the colon and rectal surgery department of our hospital

Exclusion criteria

  • Cases in which there is a sudden change of surgery plans, or those in which consent forms are retracted.

Trial design

22 participants in 1 patient group

HIPEC cytoreductive surgery
Treatment:
Drug: HIPEC cytoreductive surgery

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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