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The Investigation of a Fluorescence/Elastic Scattering Spectroscopy (F-ESS) Device for Oral Tissue Characterization

University of California Irvine (UCI) logo

University of California Irvine (UCI)

Status

Completed

Conditions

Other Lesions of Oral Mucosa

Treatments

Device: Fluorescence/Elastic Scattering Spectroscopy

Study type

Observational

Funder types

Other

Identifiers

NCT00764569
20086355

Details and patient eligibility

About

The overall objective of this work is to identify changes in the optical properties of oral tissues to develop a non-invasive tool for the detection, diagnosis and screening of oral pathology so that treatment can be provided at the earliest possible time.

Full description

Specifically, we will be obtaining optical spectroscopic data using a fiber optic contact probe that exploits elastic-scattering spectroscopy and fluorescence spectroscopy. Both of these technique have independently shown to provide signatures for the onset of cancer, with varied success. The purpose of this effort is to combine the two techniques and develop and understanding of the signatures obtained in both normal and abnormal oral tissue with simultaneous collection of these optical signatures.

Enrollment

77 patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • adult over 18 years of age

Exclusion criteria

  • younger than 18 years of age

Trial design

77 participants in 1 patient group

Oral Tissue measurement
Description:
Fluorescence/Elastic Scattering Spectroscopy Oral tissue measurement
Treatment:
Device: Fluorescence/Elastic Scattering Spectroscopy

Trial contacts and locations

2

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Data sourced from clinicaltrials.gov

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