The Italian Transthyretin Amyloidosis Web-Network (ITA-WebNet)

Institute of Hospitalization and Scientific Care (IRCCS)

Status: Enrolling

Conditions: ATTR Amyloidosis

Study type: Observational

Funder types: Other

Identifiers

NCT05444920

AC-019-IT

Details and patient eligibility

About

The study aims, by generating a large registry of patients with ATTR amyloidosis, including data at diagnosis and during follow up, to describe the natural history of ATTR amyloidosis in a real-world setting and to define and validate prognostic models, response criteria applicable at any point of the disease. The registry will also be used for data sharing and to allow the possibility of a close collaboration amongst the amyloidosis experts of the ARTC and all the physicians around the Country involved in the diagnosis and management of systemic amyloidosis. Thanks to the online registry, the diagnostic facility of the ARTC will be made available to requesting physicians.

Enrollment: 1,000 estimated patients

Sex: All

Ages: 18 to 99 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Suspected diagnosis of systemic and localized amyloidosis;
2. age .18 years;
3. ability to understand and willingness to sign an informed consent (patients who already sign informed consent for clinical data to be used in retrospective analyses will be accepted);
4. planned (or ongoing) follow-up at participating center.

Exclusion criteria

1. Diagnosis of light chain (AL) amyloidosis