The Lean Meats Mediterranean Diet Study

Purdue University

Status: Completed

Conditions: Dietary Modification; Cardiovascular Diseases

Treatments: Other: Red Meat Restricted; Other: Red Meat Rich

Study type: Interventional

Funder types: Other

Identifiers

NCT02573129

PurdueU

Details and patient eligibility

About

The purpose of the proposed research study is to assess the effects of including greater amounts of minimally processed red meat (lean pork and beef) into a Mediterranean Diet on cardiometabolic and emotional well-being.

Full description

All subjects will complete an 18-wk randomized crossover study. Following a 2-wk baseline testing period to assess cardiometabolic and emotional well-being and habitual diet, subjects will consume a Mediterranean-style, weight-maintenance diet that is either restricted or rich in lean, minimally processed red meat for 5 weeks. Following a 4-wk washout period and second 2-wk baseline testing, subjects will consume the Mediterranean Diet with the alternate predominant animal protein sources for 5 weeks. Cardiometabolic and emotional well-being will be assessed during baseline and post periods.

Enrollment: 41 patients

Sex: All

Ages: 30 to 69 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Male or female 30-69 years old
• BMI 25-37 kg/m2
• Total cholesterol <240 mg/dL
• Low-density lipoprotein <160 mg/dL
• Triglycerides <400 mg/dL
• Fasting glucose <110 mg/dL
• Systolic blood pressure <160 mmHg
• Diastolic blood pressure <100 mmHg
• Body weight <300 lb
• Weight stable for 3 months prior (±10 lb)
• Stable physical activity regimen 3 months prior ≤3 h/wk of moderate or high intensity exercise resistance or aerobic training
• Medication use stable for 6 months prior.

Exclusion criteria

• Diabetic
• Smoker

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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41 participants in 2 patient groups

Red Meat Restricted

Experimental group

Description:

Following a 2-wk baseline testing period to assess cardiometabolic and emotional well-being and habitual diet, subjects will consume a Mediterranean-style, weight-maintenance diet that is restricted in lean, minimally processed red meat for 5 weeks.

Treatment:

Other: Red Meat Rich

Other: Red Meat Restricted

Red Meat Rich

Experimental group

Description:

Following a 4-wk wash out period and a 2-wk baseline testing period to assess cardiometabolic and emotional well-being and habitual diet, subjects will consume a Mediterranean-style, weight-maintenance diet that is rich in lean, minimally processed red meat for 5 weeks.

Treatment:

Other: Red Meat Rich

Other: Red Meat Restricted