The Link Between Diets and Health Indicators (DIETE)

University of Primorska

Status: Completed

Conditions: Healthy Diet; Microbiota

Treatments: Behavioral: Regular lifestyle in different circumstances

Study type: Observational

Funder types: Other

Identifiers

NCT04347213

DIETE

Details and patient eligibility

About

The cohort study investigates the effect of different dietary intake among omnivorous, vegan, vegetarian and low-carb diets on health parameters and on long-term overall health. The participants blood parameters, dietary intake, gut microbiota composition, body mass and composition, resting energy expenditure, lifestyle factors and psychological factors will be determined and measured.

Full description

Vegetarian and vegan diets have been shown to have health benefits on preventing cardiovascular diseases, type 2 diabetes and cancer. They are both gaining popularity in public. Ketogenic diet has also been very popular, especially due to its effect on weight loss and blood glucose parameters. To our knowledge there, are no studies that compare long-term effects of all three diets and omnivorous diets with regards to health parameters and gut microbiota composition.

The aim of the proposed study is to investigate the link between different diets and health parameters, such as parameters related to longevity, inflammation, stress and gut microbiota composition. The study is designed to compare different diets and their relationship with the body as a whole.

Enrollment: 200 patients

Sex: All

Ages: 20 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 18,5 < BMI < 30 kg/m2
• asymptomatic for any disease
• medication free
• same pattern of eating in the last 3 months
• stable body mass in the last 3 months

Exclusion criteria

• BMI < 18,5 and > 30 kg/m2
• presence of any chronic disease
• taking any medications
• changed eating pattern in the last 3 months
• unstable body mass in the last 3 months
• taking antibiotics in the last 3 months

Trial design

200 participants in 4 patient groups

omnivors

Description:

Participants who habitually consume all food groups in their diet.

Treatment:

Behavioral: Regular lifestyle in different circumstances

vegetarian

Description:

Participants who habitually avoid meat in their diet.

Treatment:

Behavioral: Regular lifestyle in different circumstances

vegan

Description:

Participants who habitually avoid all animal source food in their diet.

Treatment:

Behavioral: Regular lifestyle in different circumstances

low-carbohydrate high-fat diet

Description:

Participants who habitually avoid carbohydrate in their diet.

Treatment:

Behavioral: Regular lifestyle in different circumstances