The Long Term Impact of Initiating Pramipexole Versus Levodopa in Early Parkinson's Disease (CALM-PD Cohort Study)

University of Rochester

Status: Terminated

Conditions: Parkinson's Disease

Treatments: Other: No intervention.

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT00804479

PPXAPD-0072-138

RSRB #09283

Details and patient eligibility

About

To determine the long-term consequences (8 years) of initiating patients with Parkinson's disease on either pramipexole or levodopa. We hypothesize that patients initiating therapy with pramipexole compared with levodopa will demonstrate less self-reported disability as measured by the Modified Schwab and England (S/E) scale 8 years after randomization.

Enrollment: 222 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Available 301 subjects enrolled in the CALM-PD study.

Exclusion criteria

• Those not enrolled in the CALM-PD study.

Trial design

222 participants in 1 patient group

no treatment

Description:

Available 301 subjects enrolled in CALM-PD Available 82 subjects enrolled in CALM-PD imaging substudy

Treatment:

Other: No intervention.