The Longterm Risk of Advanced Colorectal Neoplasia After Colonoscopy - A Population-based Cohort Study in Hong Kong (ACNC)

The Chinese University of Hong Kong

Status: Enrolling

Conditions: Colorectal Neoplasia; Colorectal Cancer

Study type: Observational

Funder types: Other

Identifiers

NCT04815525

2020.597

Details and patient eligibility

About

The primary objective of this study is to analyze the 15-year cumulative incidence of advanced colorectal neoplasia and CRC-related mortality after the index colonoscopy.

Full description

This is a territory-wide retrospective observational cohort study using the Clinical Data Analysis and Reporting System (CDARS). We will identify patients from CDARS with colonoscopy performed from 1 January 2000 to 31 October 2020. Other relevant diagnoses, procedures, concomitant drugs, laboratory parameters and pathology results will be retrieved and studied.

Enrollment: 5,000 estimated patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. All patients with colonoscopy performed in HA hospitals during the study period would be eligible for screening.

Exclusion criteria

1. Patients with documented personal history of colorectal cancers before the study period would be excluded.

Trial design

5,000 participants in 4 patient groups

Normal finding

Description:

Colonoscopy finding normal

Hyperplastic polyps

Description:

Colonoscopy finding of hyperplastic polyps

Low-risk adenomas

Description:

Colonoscopy finding of low-risk adenomas

High-risk adenomas

Description:

Colonoscopy finding of high-risk adenomas